CHEMOTHERAPEUTICS

Cancer is a debilitating disease that still imposes a huge health and economic burden throughout the world. The number of new cancer cases, which was recorded as about 3 million in the year 2000, is expected to be 7.1 million by the year 2020. The global cancer mortality is also projected to be doubled in the next 50 years. Such alarming statistics have revitalized our ever-lost war against cancer. Till to date, a wide variety of anticancer drugs have been developed. However, the increasing trend in chemotherapy resistance, relapse of certain cancer after primary cure and the chemotherapy-induced toxicity increase the search for new chemotherapeutics. This course has been designed to discuss about the existing cancer chemotherapeutic agents, their mechanisms of action, potential toxicity, with special focus on pathophysiologic basis of carcinogenesis. In addition, this course will cover the current advances in developing novel chemotherapeutic agents. The potential and landmark achievements in cancer gene therapy and drug development by targeting cancer stem cells will be discussed.

The objectives of this course include: 1) introduction to chemotherapeutic drugs 2) introduction to different strategy to improve currently use chemotherapeutic drugs used in clinic 3) introduction to basic concept of drug delivery system and combination therapy 4) introduction to currently available targeted therapy using chemotherapeutic drugs

- 본 강의는 2학점으로서 주당 수업시간은 강의 2시간으로 진행됨 - 파워포인트 (ppt)자료를 이용하여 강의가 진행됨. - 해당 강의는 영어로 진행됨.

높은 강의 참여도를 요구하며, 능동적이 예습 복습이 요구됨

- 졸업 후 제약회사, 병원 약사, 국내 외 대학 연구소 등으로 진출 시 항암제 의약품에 대한 이해도를 높일 수 있음.